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COG133

CAT: 0026-B2969-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2969-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
COG 133 is a fragment of Apolipoprotein E (APOE) that mimics the anti-inflammatory and neuroprotective effects of the intact apoE protein. It functions through the low-density lipoprotein receptor-related protein (LRP). It reduces the symptoms of experimental autoimmune encephalomyelitis model of human multiple sclerosis, suppresses inflammation, demyelination and infiltration of cells into the spinal cord. It also acts as a non-competitive antagonist at α7 nicotinic acetylcholine receptors with an IC₅₀ of 445 nM.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36months

Alternative Products

CatalogName
464668COG133 TFA salt
SB180-25MGApolipoprotein E fragment (133-149) – COG133

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