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Doxifluridine

CAT: 0026-B2650-250Size: 250 mgDry Ice: NoHazardous: No
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CAT#:0026-B2650-250Size:250 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Doxifluridine is a fluoropyrimidine derivative that acts as an oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designed to circumvent the rapid degradation of 5-FU by dihydropyrimidine dehydrogenase in the gut wall, is converted into 5-FU in the presence of pyrimidine nucleoside phosphorylase. 5-FU interferes with DNA synthesis and subsequent cell division by reducing normal thymidine production and interferes with RNA transcription by competing with uridine triphosphate for incorporation into the RNA strand.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months