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ONC212

CAT: 0026-B2950-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2950-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ONC212 is a fluorinated imipridone analogue of ONC201. It is an activator of GPCR GPR132 and Gαq signaling, which functions as a tumor suppressor. It induces apoptosis in HPAF-II and AsPC1 cell lines at 20 μM and potently prevents colony formation at 5 μM in HPAF-II cells. It inhibits acute myeloid leukemia growth in vivo and improves overall survival in xenografted mice.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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