Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1)

Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1)

• UNSPSC Description: Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth[1][2][3].
• Target Antigen: Antibiotic; Bacterial
• Type: Reference compound
• Related Pathways: Anti-infection
• Field of Research: Infection; Cancer
• Assay Protocol: https://www.medchemexpress.com/amoxicillin-trihydrate-mixture-with-potassium-clavulanate-4-1.html
• Solubility: H2O : 2 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: OC([C@@H]1N(C2=O)[C@]([C@@H]2NC([C@@H](C3=CC=C(O)C=C3)N)=O)([H])SC1(C)C)=O.O=C([C@@H](/C(O[C@]4([H])C5)=C/CO)N4C5=O)O[K].[4].[3H2O]
• Molecular Weight: 656.70
• References & Citations: [1]Michael Spector, et al. Formulations of amoxicillin and clavulanate potassium and methods for using same. WO2013173803A2.|[2]Guo Y, et, al. Metabolic response of Lactobacillus acidophilus exposed to amoxicillin. J Antibiot (Tokyo). 2022 May;75(5):268-281.|[3]Andes D, et, al. In vivo activities of amoxicillin and amoxicillin-clavulanate against Streptococcus pneumoniae: application to breakpoint determinations. Antimicrob Agents Chemother. 1998 Sep;42(9):2375-9.|[4]Kramer MJ, et, al. Activity of oral amoxicillin, ampicillin, and oxytetracycline against infection with chlamydia trachomatis in mice. J Infect Dis. 1979 Jun;139(6):717-9.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Launched