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PIK3CB Antibody

CAT: 0013-GTR18187043Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18187043Size:100 µg
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Description
PIK3CB antibody
Product Name Alternative
Rabbit anti-PIK3CB antibody, rabbit anti-PI3K beta antibody, PKC3B. PKC3 beta, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, PI3-kinase subunit beta, PI3K-ß, PI3Kbeta, PtdIns-3-kinase subunit beta, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta, PtdIns-3-kinase subunit p110-beta, p110beta, PIK3C1
UniProt
P42338
Reactivity
Human
Immunogen
This affinity purified PIK3C-ß antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an N-terminal region of human Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform.
Target
PIK3CB
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Concentration
1.09 mg/ml
Dilution
ELISA: 1:50,000, WB: 1.0 ug/mL
Purity
Anti-PIK3C beta was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific for human PIK3C beta protein. A BLAST analysis was used to suggest cross-reactivity with PI3K-beta based on a 100% homology from human sources with the immunizing sequence. Expect partial cross reactivity to PIK3C beta from mouse and rat (93% homology) sources. Cross-reactivity with PIK3C beta from other sources has not been determined.
Form
Liquid (sterile filtered)
Storage Conditions
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Notes
For research use only.
Applications Notes
Anti-PIK3C beta Antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 122.7 kDa in size corresponding to PI3K beta by western blotting in the appropriate cell lysate or extract.
Tested Applications
ELISA, WB
NCBI Accession Number
NP_006210.1
Host or Source
Rabbit
Preservative
Preservative: 0.01% (w/v) Sodium Azide. Stabilizer: None; Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Isotype
IgG

UniProtKB · P42338

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

PK3CB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P42338
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PIK3CB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PI3-kinase subunit beta, PI3K-beta, PI3Kbeta, PtdIns-3-kinase subunit beta
EC number
2.7.1.153
Processing
—
Secondary accessions
D3DNF0, Q24JU2
Protein keywords

Ligand

ATP-bindingNucleotide-binding

Biological process

AutophagyCell adhesionEndocytosisLipid metabolism

Cellular component

CytoplasmNucleus

Molecular function

KinaseTransferase

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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