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Recombinant HER2 Fab Antibody

CAT: 0013-GTR18186988Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18186988Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HER2 Fab antibody
Product Name Alternative
CD340, cluster of differentiation 340, ERBB2 (human), human epidermal growth factor receptor 2, HER2/neu, recombinant Monoclonal HER2, RabMAb HER2, Trastuzumab, Herceptin, Humanized Antibody, Recombinant Anti-HER2 Fab antibody, HER-2, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, Proto-oncogene Neu, p185erbB2
UniProt
P04626
Reactivity
Human
Target
ERBB2
Clonality
Recombinant
Clone
Abz518
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Concentration
0.59 mg/ml
Dilution
ELISA: 1:10,000 to 1:100,000, FC: 1:100, WB: 1:2,000
Purity
Humanized Recombinant HER2 Fab fragment was expressed in E. coli cells. The purity was estimated to be > 90% by SDS-PAGE analysis.
Form
Liquid (sterile filtered)
Storage Conditions
Store vial at 2-8° C. Dilute only prior to immediate use.
Notes
For research use only.
Applications Notes
Humanized Recombinant Anti-HER2 Fab fragment Antibody has been tested for use in Flow Cytometry, Western Blot, and ELISA. This antibody recognizes structured HER2 and will work in western blot when the protein has not been denatured with DTT or bMe. Although not tested, this antibody could be useful in in IHC and in in-vivo and other cellular assays. Specific conditions for reactivity should be optimized by the end user.
Tested Applications
ELISA, FC, WB
NCBI Accession Number
NP_001005862.1
Preservative
Preservative: 0.01% (w/v) Sodium Azide. Stabilizer: 30% Glycerol; Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Isotype
IgG Fab

UniProtKB · P04626

Receptor tyrosine-protein kinase erbB-2

ERBB2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04626
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ERBB2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.10.1
Processing
Precursor
Secondary accessions
B2RZG3, B4DHN3, Q14256, Q6LDV1, Q9UMK4, X5D2V5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorKinaseReceptorTransferaseTyrosine-protein kinase

Coding sequence diversity

Alternative initiationAlternative splicingChromosomal rearrangement

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneCell projectionCytoplasmEndosomeMembraneNucleus

Disease

Disease variant

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

SignalTransmembraneTransmembrane helix

Biological process

TranscriptionTranscription regulation

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