Products for Research Use Only
RegisterLogin

Denbufylline

CAT: 0804-HY-130786Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-130786Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Denbufylline (BRL 30892) is an inhibitor of phosphodiesterase-4 (PDE4) . Denbufylline is able to block the degradation of intracellular cAMP (cyclic adenosine phosphate) thereby increasing the level of intracellular cAMP, which helps regulate a variety of cellular functions. Denbufylline can be used in the study of chronic obstructive pulmonary disease (COPD), asthma and other inflammatory diseases[1].
CAS Number
57076-71-8
Product Name Alternative
BRL 30892
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Others
Assay Protocol
https://www.medchemexpress.com/denbufylline.html
Purity
99.92
Solubility
DMSO : 33 mg/mL (ultrasonic; warming)
Smiles
O=C(N1CCCC)N(CCCC)C2=C(N(CC(C)=O)C=N2)C1=O
Molecular Formula
C16H24N4O3
Molecular Weight
320.39
References & Citations
[1]Martin L, et al. Sustained buccal delivery of the hydrophobic drug denbufylline using physically cross-linked palmitoyl glycol chitosan hydrogels[J]. European journal of pharmaceutics and biopharmaceutics, 2003, 55 (1) : 35-45.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3

Alternative Products

CatalogName
BA8227-5Denbufylline
MBS6054882-01Denbufylline (1,3-Di-n-butyl-7-[2'-oxopropyl)xanthine)
D2743Denbufylline (1,3-Di-n-butyl-7-[2’-oxopropyl) xanthine)

Popular Products