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Iboxamycin

CAT: 0804-HY-139798-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-139798-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Iboxamycin is a potent antibiotic candidate bearing a fused bicyclic amino acid residue. Iboxamycin is orally bioavailable, safe and effective in researching both Gram-positive and Gram-negative bacterial infections in mice[1][2].
CAS Number
2640000-92-4
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/iboxamycin.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](NC1)[C@@](OCC2)([H])[C@@]1([H])C[C@@H]2CC(C)C)N[C@@H]([C@@]([C@@H]([C@@H]3O)O)([H])O[C@@H]([C@@H]3O)SC)[C@@H](Cl)C
Molecular Formula
C22H39ClN2O6S
Molecular Weight
495.07
References & Citations
[1]Mason JD, et al. Practical Gram-Scale Synthesis of Iboxamycin, a Potent Antibiotic Candidate. J Am Chem Soc. 2021;143 (29) :11019-11025. |[2]Mitcheltree MJ, et al. A synthetic antibiotic class overcoming bacterial multidrug resistance. Nature. 2021;599 (7885) :507-512.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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