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Nirvanol-d5

CAT: 0804-HY-W012481S-01Size: 2.5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W012481S-01Size:2.5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nirvanol-d5 (Ethylphenylhydantoin-d5) is deuterium labeled Nirvanol. Nirvanol (Ethylphenylhydantoin) is a metabolite of Mephenytoin (HY-B1184) that exerts anticonvulsant effects in the maximal electroshock (M.E.S.) seizure model in mice. Nirvanol shows potential for research in epilepsy-related neurological disorders[2].
CAS Number
119458-27-4
Product Name Alternative
Ethylphenylhydantoin-d5; Phenylethyihydantoin-d5; Desmethylmephenytoin-d5
UNSPSC
12352005
Target
Drug Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
CCC1(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C(NC(N1)=O)=O
Molecular Formula
C11H7D5N2O2
Molecular Weight
209.26
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Kupferberg HJ, et al. The metabolism of 3-methyl-5-ethyl-5-phenylhydantoin (mephenytoin) to 5-ethyl-5-phenylhydantoin (Nirvanol) in mice in relation to anticonvulsant activity. Drug Metab Dispos. 1975 Jan-Feb;3 (1) :26-9. PMID: 234831.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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Alternative Products

CatalogName
OR1006229Nirvanol
D3220-88VRac N-Desmethyl Mephenytoin ((+/-) -Nirvanol, (+/-) -5-Ethyl-5-phenylhydantoin)
MBS6083798-01rac N-Desmethyl Mephenytoin ((+/-)-Nirvanol, (+/-)-5-Ethyl-5-phenylhydantoin)
D3220-88YS- (+) -N-Desmethylmephenytoin (S- (+) -Nirvanol, S- (+) -5-Ethyl-5-phenylhydantoin)
MBS6025555-01S-(+)-N-Desmethylmephenytoin (S-(+)-Nirvanol, S-(+)-5-Ethyl-5-phenylhydantoin)
MBS6067067-01R-(-)-N-Desmethylmephenytoin (R-(-)-Nirvanol, R-(-)-5-Ethyl-5-phenylhydantoin)
CS-EL-00084Phenoxybenzamine-d5 (Phenoxy-D5)
TRC-S211421-5MGSebuthylazine-d5 (ethyl-d5)
TMIJ-0480-01Terbutryn-d5 (ethyl-d5)
TRC-F279491-0.5MGFenuron-d5 (phenyl-d5)

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