Products for Research Use Only
RegisterLogin

PDDHV

CAT: 0804-HY-130358Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-130358Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PDDHV is a calcium absorption inducer and may achieve 45Ca2+ influx by stimulating vanillic acid receptor VR1. PDDHV induces 45Ca2+ uptake (EC50: 70 nM) in rat dorsal root ganglion neurons (expressing native vanilloid receptors) and calcium mobilization (EC50: 125 nM) in VR1-transfected CHO cells. PDDHV also inhibits [3H]-resiniferatoxin (RTX) binding to the dorsal root ganglion membrane in rats[1].
CAS Number
179469-40-0
UNSPSC
12352005
Hazard Statement
H301-H312-H330-H410
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pddhv.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC(C[C@]12O)=C[C@]([C@@](C3(C)C)([H])[C@@]3(OC(CCCCCCCCC)=O)[C@H](OC(CCCCCCCCC)=O)[C@H]4C)([H])[C@@]4(O)[C@]2([H])C=C(C)C1=O)CC5=CC=C(O)C(OC)=C5
Molecular Formula
C49H72O11
Molecular Weight
837.09
Precautions
P264-P270-P330-P405-P501
References & Citations
[1]Szallasi A, Szabo T, Biro T, et al. Resiniferatoxin‐type phorboid vanilloids display capsaicin‐like selectivity at native vanilloid receptors on rat DRG neurons and at the cloned vanilloid receptor VR1[J]. British journal of pharmacology, 1999, 128 (2) : 428-434.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19190896PDDHV

Popular Products