Lapachol (Standard)

CAT: 0804-HY-N6961RSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-N6961RSize:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Lapachol (Standard) is the analytical standard of Lapachol. This product is intended for research and analytical applications. Lapachol, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity[1][2][3].
CAS Number
[84-79-7]
UNSPSC
12352005
Target
Dihydroorotate Dehydrogenase; DNA/RNA Synthesis; Parasite; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lapachol-standard.html
Smiles
O=C(C(CC=C(C)C)=C1O)C2=CC=CC=C2C1=O
Molecular Formula
C15H14O3
Molecular Weight
242.27
References & Citations
[1]Raphael S Peres, et al. Lapachol, a compound targeting pyrimidine metabolism, ameliorates experimental autoimmune arthritis. Arthritis Res Ther. 2017 Mar 7;19 (1) :47.|[2]Masayo Maeda, et al. Promotion or suppression of experimental metastasis of B16 melanoma cells after oral administration of lapachol. Toxicol Appl Pharmacol. 2008 Jun 1;229 (2) :232-8.|[3]Iasmin Aparecida Cunha Araújo, et al. Efficacy of lapachol on treatment of cutaneous and visceral leishmaniasis. Exp Parasitol. 2019 Apr:199:67-73.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-N6961-01Lapachol
HY-13555R-01β-Lapachone (Standard)
HY-B0198R-01Cefaclor (Standard)
HY-17507R-01Pantoprazole (Standard)
HY-B1494RPicrotoxinin (Standard)
HY-A0059R-01Nifuratel (Standard)
HY-10993R-01Adavosertib (Standard)
HY-B1074R-01Ethamsylate (Standard)
HY-119335RCyphenothrin (Standard)
HY-N0181R-01Ergosterol (Standard)

Alternative Products

CatalogName
MBS3609171-01Lapachol
abx098967-01Standard
ST-08004-02Ascorbic Acid Standard + Gallic Acid Standard + TROLOX Standard + BRS Electrolyte
ST-80004-01Ascorbic Acid Standard + Gallic Acid Standard + TROLOX Standard for biological samples
RE21029ARAb Standard A (Standard 0) 20 ml

Popular Products