Anti-ECS Antibody, Agarose immobilized

• Description:

  Goat Polyclonal Antibody specific to Agarose Immobilized Goat ECS

• Product Name Alternative:

  Anti-Agarose Immobilized Goat ECS Goat Polyclonal Antibody

• Gene ID:

  5651

• UniProt:

  P98073

• Cellular Locus:

  Membrane, Single-pass type II membrane protein

• Host:

  Goat

• Reactivity:

  Ecs

• Immunogen:

  DDDDK conjugated to KLH.

• Target:

  ECS, Agarose immobilized

• Clonality:

  Polyclonal

• Isotype:

  Whole IgG

• Type:

  Antibody

• Applications:

  IP

• Field of Research:

  Epitope Tags

• Purification Method:

  Purified by peptide immuno-affinity chromatography

• Concentration:

  Lot Specific

• Dilution:

  Dilute in PBS or medium that is identical to that used in the assay system.

• Format:

  Purified

• Form:

  Liquid

• Buffer:

  Phosphate Buffered Saline

• Function:

  Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.

• Additionnal Information:

  Immunoprecipitation: use 15-25ul of gel slurry per 0.1-1mg of protein extract or lysate.
  
  These are recommended concentrations.
  
  End users should determine optimal concentrations for their applications.

• Storage Conditions:

  This antibody is stable for at least one (1) year at 2-8°C.

• Specificity:

  Antibody was affinity-purified on the peptide.

• Formulation:

  Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide

• Target Background:

  Enterokinase, also known as enteropeptidase, is a serine protease that catalyzes the hydrolysis of peptide bonds in proteins but, unlike other kinases, does not catalyze transfer of phosphate groups. Enterokinase cleaves proteins following a lysine at an enterokinase cleavage site, or ECS (Asp-Asp-Asp-Asp-Lys). In vivo, this cleavage results in trypsin-dependent activation of other pancreatic zymogens, such as chymotrypsinogen, proelastase, procarboxypeptidase and prolipase in the lumen of the gut.

• CAS Number:

  9007-83-4