Products for Research Use Only
RegisterLogin

Cyclin T2 rabbit pAb

CAT: 0855-ES17150-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES17150-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
Description
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010],
UniProt
O60583
Swiss Prot
O60583
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human Cyclin T2 AA range: 510-590
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; WB
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, WB 1:500-2000
Molecular Weight
73kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
73kD
Fragment
IgG
Subcellular Location
Cytoplasm, perinuclear region . Nucleus . Nucleus in differentiating cells. .
Other Product Names
Cyclin-T2 (CycT2)
Gene ID (Human)
905

UniProtKB · O60583

Cyclin-T2

CCNT2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O60583
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CCNT2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CycT2
EC number
—
Processing
—
Secondary accessions
A8KA48, D3DP73, D3DP74, O60582, Q29R66, Q53SR4, Q5I1Y0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell cycleCell divisionHost-virus interactionTranscriptionTranscription regulation

Molecular function

Cyclin

Cellular component

CytoplasmNucleus

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Related Products

CatalogName
ES5568-01Gα t2 rabbit pAb
ES2078-01Cyclin A rabbit pAb
ES7862-01β-1,4-Gal-T2 rabbit pAb
ES7863-01β-1,3-Gal-T2 rabbit pAb
ES2088-01Cyclin M2 rabbit pAb
ES2079-01Cyclin A1 rabbit pAb
ES2085-01Cyclin G rabbit pAb
ES2082-01Cyclin E1 rabbit pAb
ES7910-01Cyclin C rabbit pAb
ES2086-01Cyclin H rabbit pAb

Alternative Products

CatalogName
MBS8541687-01Cyclin A Rabbit pAb
MBS225052-01Rabbit anti CYCLIN-A
YP-W73969-01Rabbit Cyclin-D1 (Cyclin-D1) ELISA Kit
NBP3-21690-100ulRabbit Monoclonal Cyclin A1/Cyclin A2 Antibody (SR1909)
NBP3-16140-20ulRabbit Monoclonal Cyclin A1/Cyclin A2 Antibody (10O1C8)
E56G3637Phospho-Cyclin D1 /Cyclin D2 Rabbit Monoclonal Antibody
APA5253-01Cyclin D1 Rabbit pAb
APA5161-01Cyclin A2 Rabbit pAb
APA4787-01Cyclin B1 Rabbit pAb
APA4290-01Cyclin H Rabbit pAb

Popular Products