Cyclin T2 rabbit pAb
CAT:
855-ES17150-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Cyclin T2 rabbit pAb
- Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010],
- Synonyms: Cyclin-T2 (CycT2)
- Gene ID: 905
- UniProt: O60583
- Cellular Locus: Cytoplasm, perinuclear region. Nucleus. Nucleus in differentiating cells..
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Synthesized peptide derived from human Cyclin T2 AA range: 510-590
- Clonality: Polyclonal
- Validated Applications: IHC, IF, WB
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: IHC-p 1:50-200, WB 1:500-2000
- Molecular Weight: 73kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.