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Quinovic acid

CAT: 0804-HY-N1524-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1524-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Quinovic acid is triterpene. Quinovic acid can ameliorate the Amyloid-β burden, p53 expression and cholesterol accumulation by deterring the oxidative stress through upregulating the Nrf2/HO-1 pathway. Quinovic acid can induce cancer cells apoptosis by upregulating death receptor 5 (DR5) . Quinovic acid can be used for the researches of cancer, inflammation, metabolic and neurological disease, such as lung cancer and Alzheimer’s disease (AD) [1][2].
CAS Number
465-74-7
UNSPSC
12352211
Target
Amyloid-β; Apoptosis; MDM-2/p53
Type
Natural Products
Related Pathways
Apoptosis; Neuronal Signaling
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/quinovic-acid.html
Purity
96.0
Solubility
10 mM in DMSO
Smiles
OC([C@@]12C([C@@]3([H])[C@@](CC2)(CC[C@H]([C@@H]3C)C)C(O)=O)=CC[C@@]4([H])[C@]1(CC[C@]5([H])[C@@]4(CC[C@@H](C5(C)C)O)C)C)=O
Molecular Formula
C30H46O5
Molecular Weight
486.68
References & Citations
[1]Saeed K, et al. Quinovic Acid Impedes Cholesterol Dyshomeostasis, Oxidative Stress, and Neurodegeneration in an Amyloid-β-Induced Mouse Model. Oxid Med Cell Longev. 2020 Nov 20;2020:9523758.|[2]Khayam AU, et al. Quinovic acid purified from medicinal plant Fagonia indica mediates anticancer effects via death receptor 5. Mol Cell Biochem. 2020 Nov;474 (1-2) :159-169.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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T4366-01Quinovic acid
MQ44392-01Quinovic acid 3-O-a-L-rhamnopyranoside
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TN4887Quinovic acid 3-O-beta-D-glucoside
MQ44371-01Quinovic acid 3-O-b-D-glucoside
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