Aganodine

• Description :

  Aganodine is a guanidine that activates presynaptic imidazoline receptors and can inhibit electrically evoked [3H]-norepinephrine release[1][2][3].

• CAS Number :

  [86696-87-9]

• UNSPSC :

  12352005

• Target :

  Imidazoline Receptor

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/aganodine.html

• Smiles :

  ClC1=CC=C(C2=C1CN(C2)NC(N)=N)Cl

• Molecular Formula :

  C9H10Cl2N4

• Molecular Weight :

  245.11

• References & Citations :

  [1]Molderings G J, et al. Presynaptic imidazoline receptors and non‐adrenoceptor [3H]‐idazoxan binding sites in human cardiovascular tissues[J]. British journal of pharmacology, 1997, 122 (1) : 43-50.|[2]Göthert M, et al. α2‐Adrenoceptor‐independent inhibition by imidazolines and guanidines of noradrenaline release from peripheral, but not central noradrenergic neurons[J]. Annals of the New York Academy of Sciences, 1995, 763 (1) : 405-419.|[3]Schlicker E, et al. Effects of imidazolines in noradrenaline release in brain: An investigation into their relationship to imidazoline, α2 and H3 receptors[J]. Neurochemistry international, 1997, 30 (1) : 73-83.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported