Aganodine

CAT: 0804-HY-106504Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-106504Size:1 Each

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Description

Aganodine is a guanidine that activates presynaptic imidazoline receptors and can inhibit electrically evoked [3H]-norepinephrine release[1][2][3].

CAS Number

86696-87-9

UNSPSC

12352005

Target

Imidazoline Receptor

Type

Reference compound

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/aganodine.html

Smiles

ClC1=CC=C(C2=C1CN(C2)NC(N)=N)Cl

Molecular Formula

C9H10Cl2N4

Molecular Weight

245.11

References & Citations

[1]Molderings G J, et al. Presynaptic imidazoline receptors and non‐adrenoceptor [3H]‐idazoxan binding sites in human cardiovascular tissues[J]. British journal of pharmacology, 1997, 122 (1) : 43-50.|[2]Göthert M, et al. α2‐Adrenoceptor‐independent inhibition by imidazolines and guanidines of noradrenaline release from peripheral, but not central noradrenergic neurons[J]. Annals of the New York Academy of Sciences, 1995, 763 (1) : 405-419.|[3]Schlicker E, et al. Effects of imidazolines in noradrenaline release in brain: An investigation into their relationship to imidazoline, α2 and H3 receptors[J]. Neurochemistry international, 1997, 30 (1) : 73-83.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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GTR19200562-01	Aganodine

Aganodine

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