PI3Kα-IN-4
CAT:
804-HY-131345-05
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PI3Kα-IN-4
- CAS Number: 2322293-83-2
- UNSPSC Description: PI3Kα-IN-4 is a potent, selective and orally active inhibitor of PI3Kα, with an IC50 of 1.8 nM. PI3Kα-IN-4 has antitumor activity[1].
- Target Antigen: PI3K
- Type: Reference compound
- Related Pathways: PI3K/Akt/mTOR
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/pi3kα-in-4.html
- Purity: 99.76
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(NC)[C@H](C)CN1C=NC2=C(C=C(C3=CC(NS(=O)(C4=CC=C(F)C=C4Cl)=O)=C(OC)N=C3)C=C2)C1=O
- Molecular Weight: 560.00
- References & Citations: [1]Dong J, et, al. Discovery of 3-Quinazolin-4(3 H)-on-3-yl-2, N-dimethylpropanamides as Orally Active and Selective PI3Kα Inhibitors. ACS Med Chem Lett. 2020 Jun 10; 11(7): 1463-1469.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported