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Rafabegron

CAT: 0804-HY-122120-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-122120-01Size:1 mg
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Description
Rafabegron (AJ-9677) is a specific beta3-adrenoceptor agonist. Rafabegron can reduce blood glucose, insulin, FFA, and triglyceride levels in diabetic and obese mouse models[1].
CAS Number
244081-42-3
Product Name Alternative
AJ‐9677
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/rafabegron.html
Solubility
10 mM in DMSO
Smiles
OC(COC1=C2C(C(C[C@@H](C)NC[C@@H](C3=CC(Cl)=CC=C3)O)=CN2)=CC=C1)=O
Molecular Formula
C21H23ClN2O4
Molecular Weight
402.87
References & Citations
[1]H Kato, et al. Mechanism of amelioration of insulin resistance by beta3-adrenoceptor agonist AJ-9677 in the KK-Ay/Ta diabetic obese mouse model. Diabetes. 2001, 50, 1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
GTR19192958-01Rafabegron

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