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Triamcinolone

CAT: 0804-HY-B0328-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0328-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Triamcinolone is a long-acting corticosteroid with anti-inflammatory, anti-oedematous, anti-proliferative, anti-angiogenetic, immunomodulatory and neuroprotective effects through binding to glucocorticoid receptors. Triamcinolone can relieve several dermatitis, immune diseases and ocular diseases[1][2].
CAS Number
124-94-7
UNSPSC
12352211
Hazard Statement
H351
Target
Glucocorticoid Receptor; Interleukin Related
Type
Natural Products
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Endocrinology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Triamcinolone.html
Concentration
10mM
Purity
99.86
Solubility
DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL
Smiles
F[C@@]1([C@]2(C=C3)C)[C@](CCC2=CC3=O)([H])[C@@](C[C@@H](O)[C@]4(O)C(CO)=O)([H])[C@]4(C)C[C@@H]1O
Molecular Formula
C21H27FO6
Molecular Weight
394.43
Precautions
H351
References & Citations
[1]McAlindon TE, et al. Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients With Knee Osteoarthritis: A Randomized Clinical Trial. JAMA. 2017;317 (19) :1967-1975.|[2]Spandau UH, et al. Effect of triamcinolone acetonide on proliferation of retinal endothelial cells in vitro and in vivo. Br J Ophthalmol. 2005 Jun;89 (6) :745-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched

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