Phenylhydroquinone

• UNSPSC Description:

  Phenylhydroquinone (PHQ) is an orally active thymic atrophy inducer which can up-regulate apoptosis through activation of p53. PHQ can be used for research of thymic atrophy[1].

• Target Antigen:

  ERK; MDM-2/p53; p38 MAPK

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;MAPK/ERK Pathway;Stem Cell/Wnt

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/phenylhydroquinone.html

• Purity:

  99.21

• Solubility:

  10 mM in DMSO

• Smiles:

  OC1=CC(C2=CC=CC=C2)=C(O)C=C1

• Molecular Weight:

  186.21

• References & Citations:

  [1]Nakata Y, et al. Phenylhydroquinone induces loss of thymocytes through cell cycle arrest and apoptosis elevation in p53-dependent pathway. J Toxicol Sci. 2013;38(3):325-35.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1079-21-6