Efdamrofusp alfa

• Description:

  Efdamrofusp alfa is a bispecific fusion protein. Efdamrofusp alfa is capable of neutralizing both VEGF isoforms and C3b/C4b. Efdamrofusp alfa can be used for the research of neovascular age-related macular degeneration (nAMD) and other complement-related ocular conditions[1].

• Product Name Alternative:

  IBI302

• UNSPSC:

  12352203

• Target:

  VEGFR

• Type:

  Inhibitory Antibodies

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/efdamrofusp-alfa.html

• Purity:

  99.89

• Solubility:

  10 mM in DMSO

• Smiles:

  [Efdamrofusp alfa]

• Molecular Weight:

  (140.4 kDa)

• References & Citations:

  [1]Shiqi Yang, et al. Targeting C3b/C4b and VEGF with a bispecific fusion protein optimized for neovascular age-related macular degeneration therapy. Sci Transl Med. 2022 Jun;14 (647) :eabj2177.

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  Store at -80°C for 2 years

• Scientific Category:

  Inhibitory Antibodies

• Clinical Information:

  No Development Reported

• CAS Number:

  2375661-82-6