6PPD

• Description:

  6PPD is a rubber antioxidant that scavenges ozone, forming nitroxyl radicals. 6PPD exposure decreases hatchability, lowered autonomous movement, reduces body length in zebrafish embryos and causes deformities. 6PPD also produces oxidative stress in zebrafish embryos[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H317, H410

• Target:

  Reactive Oxygen Species (ROS)

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/6ppd.html

• Purity:

  99.44

• Solubility:

  DMSO : 200 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  CC(C)CC(NC1=CC=C(NC2=CC=CC=C2)C=C1)C

• Molecular Formula:

  C18H24N2

• Molecular Weight:

  268.40

• Precautions:

  H302, H317, H410

• References & Citations:

  [1]Peng W, et al. Exposure to N- (1,3-dimethylbutyl) -N'-phenyl-p-phenylenediamine (6PPD) affects the growth and development of zebrafish embryos/larvae. Ecotoxicol Environ Saf. 2022 Mar 1;232:113221.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  793-24-8