D-Cystine

• Description:

  D-Cystine is the D-enantiomer of L-Cystine. D-Cystine inhibits L-aspartate-β-semialdehyde dehydrogenase (ASADH) from Escherichia coli[1].

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Antibiotic; Bacterial; Drug Isomer

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/d-cystine.html

• Purity:

  98.0

• Solubility:

  DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 5.56 mg/mL (ultrasonic; warming; adjust pH to 9 with 1 M NaOH; heat to 60°C)

• Smiles:

  OC([C@H](N)CSSC[C@@H](N)C(O)=O)=O

• Molecular Formula:

  C6H12N2O4S2

• Molecular Weight:

  240.30

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Emilio Alvarez, et al. L-cystine inhibits aspartate-beta-semialdehyde dehydrogenase by covalently binding to the essential 135Cys of the enzyme. Biochim Biophys Acta. 2004 Jan 14;1696 (1) :23-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  349-46-2