3-O-Methyl-DL-DOPA (Standard)

• UNSPSC Description:

  3-O-Methyl-DL-DOPA (Standard) is the analytical standard of 3-O-Methyl-DL-DOPA. This product is intended for research and analytical applications. 3-O-Methyl-DL-DOPA is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Epilepsy, Purine Nucleoside Phosphorylase Deficiency and Aromatic L Amino Acid Decarboxylase Deficiency[1][2][3][4].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Reference Standards

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/3-o-methyl-dl-dopa-standard.html

• Smiles:

  NC(CC1=CC=C(O)C(OC)=C1)C(O)=O

• Molecular Weight:

  211.21

• References & Citations:

  [1]Darin N, et al. Mutations in PROSC Disrupt Cellular Pyridoxal Phosphate Homeostasis and Cause Vitamin-B6-Dependent Epilepsy. Am J Hum Genet. 2016 Dec 1;99(6):1325-1337.|[2]Ormazabal A, et al. Pyridoxal 5'-phosphate values in cerebrospinal fluid: reference values and diagnosis of PNPO deficiency in paediatric patients. Mol Genet Metab. 2008 Jun;94(2):173-7. |[3]Abdenur JE, et al. Aromatic l-aminoacid decarboxylase deficiency: unusual neonatal presentation and additional findings in organic acid analysis. Mol Genet Metab. 2006 Jan;87(1):48-53. |[4]Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.

• Shipping Conditions:

  Room temperature

• CAS Number:

  7636-26-2