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Gartanin

CAT: 0804-HY-N6038-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N6038-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Gartanin is a natural xanthone of mangosteen, with antioxidant, anti-inflammatory, antifungal, neuroprotective and antineoplastic properties. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells[1][2].
CAS Number
33390-42-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Autophagy; Fungal
Type
Natural Products
Related Pathways
Anti-infection; Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gartanin.html
Purity
98.55
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C1C2=C(OC3=C(O)C=CC(O)=C13)C(C/C=C(C)\C)=C(O)C(C/C=C(C)/C)=C2O
Molecular Formula
C23H24O6
Molecular Weight
396.43
Precautions
H302, H315, H319
References & Citations
[1]Gao XY, et al. Gartanin Protects Neurons against Glutamate-Induced Cell Death in HT22 Cells: Independence of Nrf-2 but Involvement of HO-1 and AMPK. Neurochem Res. 2016 Sep;41 (9) :2267-77.|[2]Kim MO, et al. Gartanin induces autophagy through JNK activation which extenuates caspase-dependent apoptosis. Oncol Rep. 2015 Jul;34 (1) :139-46.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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