GARP&Latent TGF beta Complex, Mouse (Biotinylated, HEK293, His-Avi)

GARP&Latent TGF beta Complex, Mouse (Biotinylated, HEK293, His-Avi)

• UNSPSC Description: GARP/latent TGF-b1 complexes are potent inducers of Th17 differentiation in the presence of exogenous IL-6 and inducers of Treg in the presence of IL-2. GARP&Latent TGF beta Complex Protein, Mouse (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant protein (GARP (I18-N628)&TGF-b1 (L30-S390)) produced by HEK293 cells with His-Avi tag[1][2].
• Type: Recombinant Proteins
• Assay Protocol: https://www.medchemexpress.com/cytokines/garp-latent-tgf-beta-complex-protein-mouse-biotinylated-hek293-his-avi.html
• Molecular Weight: 72-76 kDa
• References & Citations: [1]Soyoung A Oh,TGF-β: guardian of T cell function. J Immunol. 2013 Oct 15;191(8):3973-9.|[2]Angela X Zhou, et al. GARP-TGF-β complexes negatively regulate regulatory T cell development and maintenance of peripheral CD4+ T cells in vivo. J Immunol. 2013 May 15;190(10):5057-64.|[3]Justin P Edwards, et al. The GARP/Latent TGF-β1 complex on Treg cells modulates the induction of peripherally derived Treg cells during oral tolerance. Eur J Immunol. 2016 Jun;46(6):1480-9.
• Shipping Conditions: Room temperature