ERCC1 Antibody (C-term) [AMM02449G]

• Synonyms:

  DNA excision repair protein ERCC-1, ERCC1

• Gene Name:

  ERCC1

• Gene ID:

  2067

• UniProt:

  P07992

• Chromosomal Location:

  [Isoform 1]: Nucleus [Isoform 3]: Nucleus

• Applications:

  WB

• Dilution:

  WB--1:2000

• Form:

  Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

• Function:

  [Isoform 1]: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL) . Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.

• Molecular Weight:

  32562

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ERCC1 Antibody (C-term) [AMM02449G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=2067

• Uniprot URL:

  https://www.uniprot.org/uniprot/P07992