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Pyrithioxin

CAT: 0804-HY-B0910-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0910-01Size:10 mg
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Description
Pyrithioxin (Pyritinol) is an orally active neurodynamic compound. Pyrithioxin can promote the metabolism of glucose and amino acids, increase carotid blood flow and improve cerebral blood flow. Pyrithioxin exhibits anti-inflammation, anti-tumor and neuroprotective effect. Pyrithioxin can be used for the researches of cancer, inflammation, immunology, metabolic and neurological disease such as cerebral infarct, epilepsy, fibrosarcomas and rheumatoid polyarthritis[1][2][3][4][5][6][7].
CAS Number
1098-97-1
Product Name Alternative
Pyritinol; Pyridoxine disulfide; Vitamin B6 disulfide
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Drug Derivative
Type
Natural Products
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Inflammation/Immunology; Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Pyrithioxin.html
Solubility
10 mM in DMSO
Smiles
OCC1=C(CSSCC2=C(CO)C(O)=C(C)N=C2)C=NC(C)=C1O
Molecular Formula
C16H20N2O4S2
Molecular Weight
368.47
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Stoica E, et al. Facilitation through hyperventilation of therapeutic effect of pyrithioxin in cerebral infarct patients. Eur Neurol. 1975;13 (4) :285-303.|[2]von Metzler A. et al. [Antineoplastic activity of drugs affecting the central nervous system against chemically induced tumors in the rat (author's transl) ]. J Cancer Res Clin Oncol. 1979 Sep;95 (1) :11-8. German.|[3]Crouzet J, et al. Pyrithioxine et polyarthrite rhumatoïde [Pyrithioxin and rheumatoid polyarthritis]. Rev Rhum Mal Osteoartic. 1986 Jan;53 (1) :45-8.|[4]Marston HM, et al. Effects of the chronic administration of pyrithioxin on behaviour and cholinergic function in young and aged rats. J Psychopharmacol. 1987 Jan;1 (4) :237-43.|[5]Zheng S, et al. Combined mutagenesis and metabolic regulation to enhance D-arabitol production from Candida parapsilosis. J Ind Microbiol Biotechnol. 2020 May;47 (4-5) :425-435.|[6]Martínez-Lage JM, et al. Asociación de piritioxina y difenilhidantoina, en el tratamiento de los síndromes epilépticos orgánicos [Association of pyrithioxin and diphenylhydantoin in the treatment of organic epileptic syndromes]. Med Clin (Barc) . 1965 Sep;45 (3) :204-5.|[7]Jiménez-Andrade GY, et al. Pyritinol reduces nociception and oxidative stress in diabetic rats. Eur J Pharmacol. 2008 Aug 20;590 (1-3) :170-6.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
Launched

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