HLA-G Antibody (Center) [APR06131G]

• Background:

  Tissue Location: Expressed in adult eye (PubMed:1570318) . Expressed in immune cell subsets including monocytes, myeloid and plasmacytoid dendritic cells and regulatory T cells (Tr1) (at protein level) (PubMed:20448110) . Secreted by follicular dendritic cell and follicular helper T cells (PubMed:24453251) . Isoform 5: Detected in physiological fluids including amniotic fluid and serum (PubMed:11137219) . Isoform 7: Expressed in placenta, amniotic membrane, skin cord blood and peripheral blood mononuclear cells (PubMed:11137219)

• Synonyms:

  HLA class I histocompatibility antigen, alpha chain G, HLA G antigen, MHC class I antigen G, HLA-G, HLA-60, HLAG

• Gene Name:

  HLA-G {ECO:0000303|PubMed:1570318, ECO:0000312|HGNC:HGNC:4964}

• Gene ID:

  3135

• UniProt:

  P17693

• Chromosomal Location:

  [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane. Early endosome membrane [Isoform 2]: Cell membrane; Single-pass type I membrane protein [Isoform 4]: Cell membrane; Single-pass type I membrane protein [Isoform 6]: Secreted Cell projection, filopodium membrane. Note=HLA-G trogocytosis from extravillous trophoblast's filopodia occurs in the majority of decidual NK cells.

• Applications:

  IHC-P-Leica, FC, WB

• Dilution:

  IHC-P-Leica--1:500 WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  231849842926234919304799758414988052472318498429262349163667341930479920448110278590422318498429262349163667341930479919304799204481102785904210190900112907822445325124453251201792722646000716809620

• Molecular Weight:

  38224

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HLA-G Antibody (Center) [APR06131G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=3135

• Uniprot URL:

  https://www.uniprot.org/uniprot/P17693