MMP12 Antibody (C-term) [APR05709G]

• Background:

  Tissue Location: Found in alveolar macrophages but not in peripheral blood monocytes

• Synonyms:

  Macrophage metalloelastase, MME, Macrophage elastase, ME, hME, Matrix metalloproteinase-12, MMP-12, MMP12, HME

• Gene Name:

  MMP12

• Gene ID:

  4321

• UniProt:

  P39900

• Chromosomal Location:

  Secreted, extracellular space, extracellular matrix

• Applications:

  WB, IF, IHC-P

• Dilution:

  WB--1:2000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.

• Molecular Weight:

  54002

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MMP12 Antibody (C-term) [APR05709G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=4321

• Uniprot URL:

  https://www.uniprot.org/uniprot/P39900