TICAM1 Antibody (N-term) [APR04591G]

• Background:

  Tissue Location: Ubiquitously expressed but with higher levels in liver.

• Synonyms:

  TIR domain-containing adapter molecule 1, TICAM-1, Proline-rich, vinculin and TIR domain-containing protein B, Putative NF-kappa-B-activating protein 502H, Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta, MyD88-3, TIR domain-containing adapter protein inducing IFN-beta, TICAM1, PRVTIRB, TRIF

• Gene Name:

  TICAM1

• Gene ID:

  148022

• UniProt:

  Q8IUC6

• Chromosomal Location:

  Cytoplasmic vesicle, autophagosome. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q80UF7}. Mitochondrion {ECO:0000250|UniProtKB:Q80UF7}. Note=Colocalizes with UBQLN1 in the autophagosome (PubMed:21695056) . Colocalizes in the cytosol with DDX1, DDX21 and DHX36. Colocalizes in the mitochondria with DDX1 and poly (I:C) RNA ligand. The multi-helicase-TICAM1 complex may translocate to the mitochondria upon poly (I:C) RNA ligand stimulation (By similarity) . {ECO:0000250|UniProtKB:Q80UF7, ECO:0000269|PubMed:21695056}

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  1247109512539043147393032874734712471095125390431473930312471095125390431473930325636800

• Molecular Weight:

  76422

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TICAM1 Antibody (N-term) [APR04591G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=148022

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8IUC6