PBP (PPBP) Antibody (C-term) [APR05933G]

• Synonyms:

  Platelet basic protein, PBP, C-X-C motif chemokine 7, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF, Small-inducible cytokine B7, Connective tissue-activating peptide III, CTAP-III, LA-PF4, Low-affinity platelet factor IV, TC-2, Connective tissue-activating peptide III (1-81), CTAP-III (1-81), Beta-thromboglobulin, Beta-TG, Neutrophil-activating peptide 2 (74), NAP-2 (74), Neutrophil-activating peptide 2 (73), NAP-2 (73), Neutrophil-activating peptide 2, NAP-2, TC-1, Neutrophil-activating peptide 2 (1-66), NAP-2 (1-66), Neutrophil-activating peptide 2 (1-63), NAP-2 (1-63), PPBP, CTAP3, CXCL7, SCYB7, TGB1, THBGB1

• Gene Name:

  PPBP

• Gene ID:

  5473

• UniProt:

  P02775

• Chromosomal Location:

  Secreted.

• Applications:

  IHC-P, WB

• Dilution:

  WB--1:1000 IHC-P--1:100~500

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Function:

  LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2 (73), NAP-2 (74), NAP-2 (1-66), and most potent NAP-2 (1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III (1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.

• Molecular Weight:

  13894

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PBP (PPBP) Antibody (C-term) [APR05933G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5473

• Uniprot URL:

  https://www.uniprot.org/uniprot/P02775