RAGE Antibody (Center) [APR05818G]

• Background:

  Tissue Location: Expressed in heart, brain, lung, kidney, and pancreas, and at very low levels in placenta, liver and skeletal muscle. Detected in retina

• Synonyms:

  MAPK/MAK/MRK overlapping kinase, MOK protein kinase, Renal tumor antigen 1, RAGE-1, MOK, RAGE, RAGE1

• Gene Name:

  MOK

• Gene ID:

  5891

• UniProt:

  Q9UQ07

• Chromosomal Location:

  Cytoplasm {ECO:0000250|UniProtKB:Q9WVS4}. Cell projection, cilium {ECO:0000250|UniProtKB:Q9WVS4}. Nucleus {ECO:0000250|UniProtKB:Q9WVS4}

• Applications:

  IF, WB

• Dilution:

  WB--1:1000 IF--1:10~50

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Able to phosphorylate several exogenous substrates and to undergo autophosphorylation. Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner.

• Molecular Weight:

  48014

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RAGE Antibody (Center) [APR05818G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5891

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UQ07