YB1 (YBX1) Antibody (N-term) [APR05739G]

• Synonyms:

  Nuclease-sensitive element-binding protein 1, CCAAT-binding transcription factor I subunit A, CBF-A, DNA-binding protein B, DBPB, Enhancer factor I subunit A, EFI-A, Y-box transcription factor, Y-box-binding protein 1, YB-1, YBX1, NSEP1, YB1

• Gene Name:

  HGNC:8014

• Gene ID:

  4904

• UniProt:

  P67809

• Chromosomal Location:

  Cytoplasm. Nucleus. Cytoplasmic granule. Secreted. Secreted, extracellular exosome Note=Predominantly cytoplasmic in proliferating cells (PubMed:12604611) . Cytotoxic stress and DNA damage enhance translocation to the nucleus (PubMed:14718551) . Localized in cytoplasmic mRNP granules containing untranslated mRNAs (PubMed:25229427) . Shuttles between nucleus and cytoplasm (PubMed:25229427) . Localized with DDX1, MBNL1 and TIAL1 in stress granules upon stress (PubMed:18335541) . Secreted by mesangial and monocytic cells after inflammatory challenges (PubMed:19483673)

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Function:

  8188694108177581169847614718551188095833135896919561594313589691081775811698476313589691902930327559612290730952834160229073095297129251260461118809583818869418809583147185511471855119483673

• Molecular Weight:

  35924

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality YB1 (YBX1) Antibody (N-term) [APR05739G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=4904

• Uniprot URL:

  https://www.uniprot.org/uniprot/P67809