ACE2 (SARS Receptor) Antibody (Center) [APR05696G]

• Background:

  Tissue Location: Expressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells (at protein level) (PubMed:15141377) . Expressed in enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level) (PubMed:15141377) Expressed in the renal proximal tubule and the small intestine (at protein level) (PubMed:18424768) . Expressed in heart, kidney, testis, and gastrointestinal system (at protein level) (PubMed:10969042, PubMed:10924499, PubMed:15231706, PubMed:12459472, PubMed:15671045, PubMed:32715618, PubMed:32170560) . In lung, expressed at low levels in some alveolar type 2 cells, the expression seems to be individual- specific (at protein level) (PubMed:32425701, PubMed:15141377, PubMed:32715618, PubMed:32170560, PubMed:33432184) . Expressed in nasal epithelial cells (at protein level) (PubMed:33432184, PubMed:32333915) Coexpressed with TMPRSS2 within some lung alveolar type 2 cells, ileal absorptive enterocytes, intestinal epithelial cells, cornea, gallbladder and nasal goblet secretory cells (PubMed:32413319, PubMed:32327758, PubMed:32358202) . Coexpressed with TMPRSS4 within mature enterocytes (PubMed:32404436) .

• Synonyms:

  Angiotensin-converting enzyme 2, ACE-related carboxypeptidase, Angiotensin-converting enzyme homolog, ACEH, Metalloprotease MPROT15, Processed angiotensin-converting enzyme 2, ACE2

• Gene Name:

  HGNC:13557

• Gene ID:

  59272

• UniProt:

  Q9BYF1

• Chromosomal Location:

  [Processed angiotensin-converting enzyme 2]: Secreted [Isoform 2]: Apical cell membrane

• Applications:

  WB, IHC-P

• Dilution:

  WB--1:1000 1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Function:

  27217402109690421092449911815627190217741450418610969042118156271181562727217402282931651842476819185582

• Molecular Weight:

  92463

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ACE2 (SARS Receptor) Antibody (Center) [APR05696G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=59272

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9BYF1