Phospho-RB (S608) Antibody [APR05147G]

• Background:

  Tissue Location: Expressed in the retina. Expressed in foreskin keratinocytes (at protein level) (PubMed:20940255)

• Synonyms:

  Retinoblastoma-associated protein, p105-Rb, pRb, Rb, pp110, RB1

• Gene Name:

  RB1

• Gene ID:

  5925

• UniProt:

  P06400

• Chromosomal Location:

  Nucleus. Note=During keratinocyte differentiation, acetylation by KAT2B/PCAF is required for nuclear localization.

• Applications:

  DB, IHC-P

• Dilution:

  DB--1:500 IHC-P--1:100~500

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is first purified by protein G affinity chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

• Function:

  1049980210499802104998021049980215084261

• Molecular Weight:

  106159

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-RB (S608) Antibody [APR05147G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5925

• Uniprot URL:

  https://www.uniprot.org/uniprot/P06400