Bixin

CAT: 0804-HY-N6884-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N6884-01Size:1 mg
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Description
Bixin is an orally active carotenoid found in the seeds of Bixa orellana. Bixin induces apoptosis in cancer cells. Bixin possessing anti-inflammatory, anti-tumor and anti-oxidant activities. Bixin treatment ameliorated cardiac dysfunction through inhibiting fibrosis, inflammation and reactive oxygen species (ROS) generation[1][2].
CAS Number
[6983-79-5]
UNSPSC
12352211
Hazard Statement
H302, H315, H319
Target
Apoptosis; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bixin.html
Purity
99.53
Solubility
DMSO : 7.14 mg/mL (ultrasonic)
Smiles
OC(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)\C=C\C(OC)=O)=O
Molecular Formula
C25H30O4
Molecular Weight
394.50
Precautions
H302, H315, H319
References & Citations
[1]Xu Z, et al. Bixin ameliorates high fat diet-induced cardiac injury in mice through inflammation and oxidative stress suppression. Biomed Pharmacother. 2017 May;89:991-1004.|[2]Kusmita L, et al. Bixa orellana L. carotenoids: antiproliferative activity on human lung cancer, breast cancer, and cervical cancer cells in vitro. Nat Prod Res. 2022 Dec;36 (24) :6421-6427.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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