ZNRF2 Antibody (N-term) [APR04679G]

• Background:

  Tissue Location: Highly expressed in the brain, with higher expression during development than in adult. Expressed also in mammary glands, testis, colon and kidney.

• Synonyms:

  E3 ubiquitin-protein ligase ZNRF2, 632-, Protein Ells2, RING finger protein 202, Zinc/RING finger protein 2, ZNRF2, RNF202

• Gene Name:

  ZNRF2

• Gene ID:

  223082

• UniProt:

  Q8NHG8

• Chromosomal Location:

  Endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein. Cell junction, synapse, presynaptic cell membrane; Peripheral membrane protein

• Applications:

  WB

• Dilution:

  WB--1:1000

• Function:

  May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

• Molecular Weight:

  24115

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ZNRF2 Antibody (N-term) [APR04679G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=223082

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8NHG8