TRAFD1 Antibody (C-term) [APR04190G]

• Synonyms:

  TRAF-type zinc finger domain-containing protein 1, Protein FLN29, TRAFD1, FLN29

• Gene Name:

  TRAFD1

• Gene ID:

  10906

• UniProt:

  O14545

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity) .

• Molecular Weight:

  64841

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TRAFD1 Antibody (C-term) [APR04190G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=10906

• Uniprot URL:

  https://www.uniprot.org/uniprot/O14545