LOXL2 Antibody (C-term) [APR04071G]

• Background:

  Tissue Location: Expressed in many tissues (PubMed:10212285) . Highest expression in reproductive tissues, placenta, uterus and prostate (PubMed:10212285) . In esophageal epithelium, expressed in the basal, prickle and granular cell layers (PubMed:22204712) . Up-regulated in a number of cancers cells and tissues.

• Synonyms:

  Lysyl oxidase homolog 2, Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14, LOXL2

• Gene Name:

  LOXL2

• Gene ID:

  4017

• UniProt:

  Q9Y4K0

• Chromosomal Location:

  Secreted, extracellular space, extracellular matrix, basement membrane. Nucleus. Chromosome. Endoplasmic reticulum. Note=Associated with chromatin (PubMed:27735137) . It is unclear how LOXL2 is nuclear as it contains a signal sequence and has been shown to be secreted (PubMed:23319596) However, a number of reports confirm its intracellular location and its key role in transcription regulation (PubMed:22204712, PubMed:22483618) .

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  27735137277351372773513725959397160966382773513724414204242392922423929228332555200268742030630021835952

• Molecular Weight:

  86725

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LOXL2 Antibody (C-term) [APR04071G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=4017

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y4K0