RBBP8 Antibody (C-term) [APR03899G]

• Background:

  Tissue Location: Expressed in ER-positive breast cancer lines, but tends to be down-regulated ER-negative cells (at protein level)

• Synonyms:

  DNA endonuclease RBBP8, 31--, CtBP-interacting protein, CtIP, Retinoblastoma-binding protein 8, RBBP-8, Retinoblastoma-interacting protein and myosin-like, RIM, Sporulation in the absence of SPO11 protein 2 homolog, SAE2, RBBP8, CTIP

• Gene Name:

  RBBP8

• Gene ID:

  5932

• UniProt:

  Q99708

• Chromosomal Location:

  Nucleus. Chromosome. Note=Associates with sites of DNA damage in S/G2 phase (PubMed:10764811, PubMed:25349192) . Ubiquitinated RBBP8 binds to chromatin following DNA damage (PubMed:16818604)

• Applications:

  WB

• Dilution:

  WB--1:2000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  17965729192021911975939520064462179657291920219119202191165817871796572919759395200644621548591516818604

• Molecular Weight:

  101942

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RBBP8 Antibody (C-term) [APR03899G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5932

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q99708