LRRC34 Antibody (Center) [APR03453G]

• Synonyms:

  Leucine-rich repeat-containing protein 34, LRRC34

• Gene Name:

  LRRC34

• Gene ID:

  151827

• UniProt:

  Q8IZ02

• Chromosomal Location:

  Nucleus {ECO:0000250|UniProtKB:Q9DAM1}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9DAM1}. Cytoplasm {ECO:0000250|UniProtKB:Q9DAM1}. Note=As stem cells differentiate, translocates from the nucleolus to the nucleus and then to the cytoplasm. Colocalizes with NPM1 and NCL in the nucleolus {ECO:0000250|UniProtKB:Q9DAM1}

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro.

• Molecular Weight:

  51277

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LRRC34 Antibody (Center) [APR03453G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=151827

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8IZ02