PCSK9 Antibody (N-term) [APR08977G]

• Background:

  Tissue Location: Expressed in neuro-epithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells

• Synonyms:

  Proprotein convertase subtilisin/kexin type 9, 3421-, Neural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9, PCSK9, NARC1

• Gene Name:

  PCSK9

• Gene ID:

  255738

• UniProt:

  Q8NBP7

• Chromosomal Location:

  Cytoplasm. Secreted. Endosome. Lysosome. Cell surface. Endoplasmic reticulum. Golgi apparatus. Note=Autocatalytic cleavage is required to transport it from the endoplasmic reticulum to the Golgi apparatus and for the secretion of the mature protein Localizes to the endoplasmic reticulum in the absence of LDLR and colocalizes to the cell surface and to the endosomes/lysosomes in the presence of LDLR. The sorting to the cell surface and endosomes is required in order to fully promote LDLR degradation

• Applications:

  WB, IHC-P, FC

• Dilution:

  WB--1:500-1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  180396581879945817461796181977022207482718660751

• Molecular Weight:

  74286

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PCSK9 Antibody (N-term) [APR08977G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=255738

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8NBP7