Pyruvate Kinase (PKM2) Antibody (C-term) [APR07169G]

• Background:

  Tissue Location: Specifically expressed in proliferating cells, such as embryonic stem cells, embryonic carcinoma cells, as well as cancer cells.

• Synonyms:

  Pyruvate kinase PKM, Cytosolic thyroid hormone-binding protein, CTHBP, Opa-interacting protein 3, OIP-3, Pyruvate kinase 2/3, Pyruvate kinase muscle isozyme, Thyroid hormone-binding protein 1, THBP1, Tumor M2-PK, p58, PKM, OIP3, PK2, PK3, PKM2

• Gene Name:

  PKM

• Gene ID:

  5315

• UniProt:

  P14618

• Chromosomal Location:

  Cytoplasm. Nucleus Note=Translocates to the nucleus in response to different apoptotic stimuli. Nuclear translocation is sufficient to induce cell death that is caspase independent, isoform-specific and independent of its enzymatic activity.

• Applications:

  IF, IHC-P, WB

• Dilution:

  WB--1:1000 IF--1:200 IHC-P--1:100~500

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Function:

  15996096185472315996096185472315996096185472318191611216201381819161117308100

• Molecular Weight:

  57937

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Pyruvate Kinase (PKM2) Antibody (C-term) [APR07169G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5315

• Uniprot URL:

  https://www.uniprot.org/uniprot/P14618