CTDSP1 Antibody (Center) [APR15594G]

• Background:

  Tissue Location: Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta

• Synonyms:

  Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, Nuclear LIM interactor-interacting factor 3, NLI-IF, NLI-interacting factor 3, Small C-terminal domain phosphatase 1, SCP1, Small CTD phosphatase 1, CTDSP1, NIF3, NLIIF, SCP1

• Gene Name:

  CTDSP1

• Gene ID:

  58190

• UniProt:

  Q9GZU7

• Chromosomal Location:

  Nucleus. Note=Colocalizes with RNA polymerase II

• Applications:

  WB

• Dilution:

  WB--1:1000

• Function:

  Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

• Molecular Weight:

  29203

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CTDSP1 Antibody (Center) [APR15594G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=58190

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9GZU7