ARG1 Antibody (C-term) [APG01977G]

• Background:

  Tissue Location: Within the immune system initially reported to be selectively expressed in granulocytes (polymorphonuclear leukocytes [PMNs]) (PubMed:15546957) . Also detected in macrophages mycobacterial granulomas (PubMed:23749634) . Expressed in group2 innate lymphoid cells (ILC2s) during lung disease (PubMed:27043409)

• Synonyms:

  Arginase-1, Liver-type arginase, Type I arginase, ARG1

• Gene Name:

  ARG1

• Gene ID:

  383

• UniProt:

  P05089

• Chromosomal Location:

  Cytoplasm. Cytoplasmic granule. Note=Localized in azurophil granules of neutrophils (PubMed:15546957)

• Applications:

  WB, IHC-P, FC

• Dilution:

  WB--1:1000 IHC-P--1:100~500 FC--1:10~50

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.

• Molecular Weight:

  34735

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ARG1 Antibody (C-term) [APG01977G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=383

• Uniprot URL:

  https://www.uniprot.org/uniprot/P05089