COTL1 Antibody (C-term) [APR15569G]

• Background:

  Tissue Location: Widely expressed with highest levels in placenta, lung, kidney and peripheral blood leukocytes and lower levels in brain, liver and pancreas.

• Synonyms:

  Coactosin-like protein, COTL1, CLP

• Gene Name:

  COTL1

• Gene ID:

  23406

• UniProt:

  Q14019

• Chromosomal Location:

  Cytoplasm. Cytoplasm, cytoskeleton. Nucleus

• Applications:

  WB, IHC-P, FC

• Dilution:

  WB--1:1000 IHC-P--1:100~500 FC--1:10~50

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis.

• Molecular Weight:

  15945

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality COTL1 Antibody (C-term) [APR15569G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=23406

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q14019