BACE2 Antibody (Center) [APR11501G]

• Background:

  Tissue Location: Brain. Present in neurons within the hippocampus, frontal cortex and temporal cortex (at protein level) . Expressed at low levels in most peripheral tissues and at higher levels in colon, kidney, pancreas, placenta, prostate, stomach and trachea. Expressed at low levels in the brain. Found in spinal cord, medulla oblongata, substantia nigra and locus coruleus. Expressed in the ductal epithelium of both normal and malignant prostate.

• Synonyms:

  Beta-secretase 2, Aspartic-like protease 56 kDa, Aspartyl protease 1, ASP1, Asp 1, Beta-site amyloid precursor protein cleaving enzyme 2, Beta-site APP cleaving enzyme 2, Down region aspartic protease, DRAP, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretase, BACE2, AEPLC, ALP56, ASP21

• Gene Name:

  BACE2

• Gene ID:

  25825

• UniProt:

  Q9Y5Z0

• Chromosomal Location:

  Cell membrane; Single-pass type I membrane protein. Golgi apparatus. Endoplasmic reticulum. Endosome

• Applications:

  WB, FC

• Dilution:

  WB--1:1000 FC--1:10~50

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

• Function:

  21907142

• Molecular Weight:

  56180

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BACE2 Antibody (Center) [APR11501G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=25825

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y5Z0