LPPR4 Antibody (C-term) [APR12455G]

• Background:

  Tissue Location: Expressed by glutamatergic neurons (at protein level) .

• Synonyms:

  Lipid phosphate phosphatase-related protein type 4, Brain-specific phosphatidic acid phosphatase-like protein 1, Plasticity-related gene 1 protein, PRG-1, LPPR4, KIAA0455, PRG1

• Gene Name:

  HGNC:23496

• Gene ID:

  9890

• UniProt:

  Q7Z2D5

• Chromosomal Location:

  Cell junction, synapse, postsynaptic density membrane; Multi-pass membrane protein

• Applications:

  WB, IHC-P, FC

• Dilution:

  WB--1:1000 IHC-P--1:100~500 FC--1:10~50

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Postsynaptic density membrane protein that indirectly regulates glutamatergic synaptic transmission through lysophosphatidic acid (LPA) -mediated signaling pathways. Binds lysophosphatidic acid (LPA) and mediates its internalization into cells. Could act as receptor or a transporter of this lipid at the post-synaptic membrane (By similarity) . Modulates lysophosphatidic acid (LPA) activity in neuron axonal outgrowth during development by attenuating phospholipid- induced axon collapse (By similarity) .

• Molecular Weight:

  82983

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LPPR4 Antibody (C-term) [APR12455G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=9890

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q7Z2D5