Phospho-DAXX (S213) Antibody [APR11160G]

• Background:

  Tissue Location: Ubiquitous.

• Synonyms:

  Death domain-associated protein 6, Daxx, hDaxx, ETS1-associated protein 1, EAP1, Fas death domain-associated protein, DAXX, BING2, DAP6

• Gene Name:

  DAXX

• Gene ID:

  1616

• UniProt:

  Q9UER7

• Chromosomal Location:

  Cytoplasm. Nucleus, nucleoplasm. Nucleus, PML body. Nucleus, nucleolus. Chromosome, centromere Note=Dispersed throughout the nucleoplasm, in PML/POD/ND10 nuclear bodies, and in nucleoli (Probable) . Colocalizes with histone H3.3, ATRX, HIRA and ASF1A at PML-nuclear bodies (PubMed:12953102, PubMed:14990586, PubMed:23222847, PubMed:24200965) . Colocalizes with a subset of interphase centromeres, but is absent from mitotic centromeres (PubMed:9645950) . Detected in cytoplasmic punctate structures (PubMed:11842083) . Translocates from the nucleus to the cytoplasm upon glucose deprivation or oxidative stress (PubMed:12968034) . Colocalizes with RASSF1 in the nucleus (PubMed:18566590) . Colocalizes with USP7 in nucleoplasma with accumulation in speckled structures (PubMed:16845383) [Isoform gamma]: Nucleus. Note=Diffuse nuclear distribution pattern and no comparable dot-like accumulation of isoform 1

• Applications:

  WB, IHC-P

• Dilution:

  WB--1:1000 IHC-P--1:100~500

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is first purified by protein G affinity chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

• Function:

  15016915

• Molecular Weight:

  81373

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-DAXX (S213) Antibody [APR11160G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=1616

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UER7