Uridine 5′-diphosphoglucose-13C6 (disodium)

• UNSPSC Description:

  Uridine 5′-diphosphoglucose-13C6 (disodium) is the 13C labeled Uridine 5′-diphosphoglucose disodium salt[1]. Uridine 5′-diphosphoglucose disodium salt (UDP-D-Glucose disodium salt) is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine-5′-diphosphoglucose is an agonist of the P2Y14 receptor, a neuroimmune system GPCR[2].

• Target Antigen:

  Endogenous Metabolite; P2Y Receptor

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  GPCR/G Protein;Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/uridine-5-diphosphoglucose-13c6-disodium.html

• Purity:

  98.35

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]1[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]([C@H]1O)COP(OP(O[13C@H]3O[13C@@H]([13C@H]([13C@@H]([13C@H]3O)O)O)[13CH2]O)(O[Na])=O)(O[Na])=O

• Molecular Weight:

  616.22

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]DietrichKeppler, et al. Uridine-5′-diphosphoglucose. Methods of Enzymatic Analysis (Second English Edition). 1974;4:2225-2228.|[3]Das A, et al. Human P2Y(14) receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups. J Med Chem. 2010 Jan 1453(1):471-80.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  2483735-04-0